Higher Early IV Fluid Rates Tied to More SIRS but Lower BUN Rise in Acute Pancreatitis: Findings From an International Cohort Presented at ACG 2025
Highlights
– In a prospective cohort from 22 international centers presented at ACG 2025, higher early intravenous fluid rates were associated with lower odds of BUN elevation but higher odds of new-onset or persistent SIRS at 6 and 24 hours after presentation.
– Each 1 mL/kg/h increase in fluid rate was linked to about 29–33% higher odds of new/persistent SIRS, while being associated with 12–17% lower odds of a BUN rise.
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.