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Higher Early IV Fluid Rates Tied to More SIRS but Lower BUN Rise in Acute Pancreatitis: Findings From an International Cohort Presented at ACG 2025

An international prospective cohort found that higher early IV fluid rates were associated with lower odds of BUN rise but higher odds of new or persistent SIRS at 6 and 24 hours after presentation, highlighting confounding issues and the n

Nov 4, 2025Sign in to read
Clinical Updates

Evaluating Hospital-Wide Use of Lactated Ringer’s Solution Versus Normal Saline: Insights from a Cluster-Randomized Crossover Trial

A large crossover trial found no significant difference in 90-day mortality or readmission when comparing hospital-wide lactated Ringer’s solution versus normal saline for intravenous fluids.

Aug 20, 2025

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