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Diabetes & Endocrinology

Discontinuous Peripheral Punctate Echogenic Foci: A Novel Ultrasound Marker Highly Suggestive of Papillary Thyroid Carcinoma

MedXY Editorial TeamAug 13, 2026
echogenic fociPapillary Thyroid Carcinomaultrasound

Highlight

This retrospective multicenter case series identified a previously undescribed ultrasound pattern—discontinuous peripheral punctate echogenic foci (DPEF)—in thyroid nodules. All nodules exhibiting this pattern were confirmed histopathologically as papillary thyroid carcinoma (PTC). This novel sonographic feature may enhance malignancy risk stratification and warrants broader recognition among thyroid imaging specialists.

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