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Vericiguat in Heart Failure with Reduced Ejection Fraction: Evidence from Pooled Analyses of VICTORIA and VICTOR Trials

MedXY Editorial Team•Oct 10, 2025•Cardiology
cardiovascular outcomesheart failurereduced ejection fractionvericiguatVICTORVICTORIA

Highlight

– Vericiguat reduces the composite risk of cardiovascular death or heart failure hospitalization in patients with HFrEF across a broad risk spectrum.
– The pooled analysis from the VICTORIA and VICTOR trials includes diverse populations with and without recent worsening of heart failure.
– Both components of the composite endpoint—cardiovascular death and heart failure hospitalization—showed statistically significant reductions.
– These findings support vericiguat as an additional treatment option in contemporary guideline-directed medical therapy for HFrEF.

Study Background

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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