Triglyceride Glucose-Waist Height Ratio Index as a Predictor of Cardiometabolic Multimorbidity in Chinese Middle-Aged and Older Adults: Insights from a National Prospective Cohort Study

Highlight

• The triglyceride glucose-waist height ratio (TyG-WHtR) index integrates metabolic and anthropometric markers, predicting cardiometabolic multimorbidity (CMM) risk.
• A prospective cohort of 4393 Chinese adults aged ≥45 showed a dose-dependent increase in CMM risk across TyG-WHtR quartiles over 9 years.
• TyG-WHtR enhanced predictive accuracy and risk reclassification beyond conventional risk factors for CMM.
• Findings support TyG-WHtR as a practical, accessible marker for early identification and prevention strategies targeting CMM in aging populations.

Background