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This review synthesizes evidence on racial disparities in prehospital trauma care, examining intervention rates, the influence of social determinants, and mortality outcomes with a focus on recent cohort data.
A large retrospective study demonstrates that transfusion of low-titer group O whole blood (LTOWB) in trauma resuscitation carries a low and comparable risk of early red blood cell alloimmunization relative to component therapy, including a
This study reveals that trauma significantly increases social risks such as food insecurity and housing instability, especially in younger adults, highlighting the need for targeted interventions to mitigate socioeconomic consequences post-
This study reveals that psychological stress, anxiety, PTSD, and military sexual trauma are linked to increased urinary incontinence severity and affect response to behavioral treatments among women veterans, underscoring the importance of
Severe trauma induces maturation and cytotoxic phenotypes in NK cells but paradoxically decreases expression of activating receptors critical for immune defense, revealing a mechanism underlying posttrauma immune dysregulation and vulnerabi
Severe trauma induces phenotypic maturation of natural killer cells but leads to a loss of key activating receptors, potentially driving posttraumatic immune dysfunction and increased infection risk.
A 2007–2019 National Trauma Data Bank analysis found ARDS incidence among ventilated trauma patients fell substantially, yet ARDS remained independently associated with increased 30‑day mortality and crude ARDS mortality rose to nearly 30%.
The FiiRST-2 trial found no superiority of clotting factor concentrates over frozen plasma for initial resuscitation in severely bleeding trauma patients, with similar transfusion needs and safety outcomes.
Intubation in the emergency department for trauma patients with active hemorrhage is associated with higher mortality, more ICU admissions, and greater transfusion needs compared to intubation in the operating room.
