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MedXY AI/MedXY News/Section: Neurology

Giving IV Thrombolysis in the Late Window Before Transfer for Thrombectomy: Improved Recanalization and 3‑Month Outcomes in a Multicenter French Cohort

MedXY Editorial Team•Dec 6, 2025•Neurology
drip-and-shipIntravenous thrombolysisstrokethrombectomy

Highlight

• IV thrombolysis (IVT) initiated beyond 4.5 hours at primary stroke centers (PSCs) before transfer for endovascular therapy (EVT) was associated with improved 3‑month modified Rankin Scale (mRS) distribution (PSOW common OR 1.97; 95% CI, 1.33–2.92).

• IVT before transfer markedly increased odds of recanalization during transfer (PSOW-OR 8.69; 95% CI, 3.16–23.87).

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