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General Surgery

Tailoring Prognostication in Pancreatic Ductal Adenocarcinoma: Impact of Neoadjuvant Therapy on Survival Predictors

Neoadjuvant therapy alters key prognostic factors in resected pancreatic ductal adenocarcinoma, enabling personalized survival prediction models distinct from chemo-naïve patients.

Oct 27, 2026
news

Age, Tumor Size, and Weight in Early-Stage Favorable Histology Wilms Tumor: Reevaluating Prognostic Indicators with COG Data

This pooled analysis from COG studies reveals that after accounting for tumor biology, age, tumor nephrectomy weight, and diameter are not independently predictive of outcomes in stage I/II favorable histology Wilms tumor, refining risk str

Oct 9, 2026Sign in to read
Allergy & Immunology

Predicting Short-Term Outcomes in Pemphigus Patients Treated with Rituximab and Glucocorticoids: Insights from a Multicenter Chinese Cohort

This multicenter retrospective study identifies key baseline predictors influencing short-term remission and relapse in pemphigus patients treated with rituximab plus glucocorticoids, guiding personalized treatment strategies.

Oct 2, 2026
Hematology-Oncology

Transforming Care in Follicular Lymphoma: Outcomes and Prognostic Insights in the Rituximab Era

This study analyzes treatment patterns, outcomes, and prognostic factors in 344 patients with transformed follicular lymphoma in the rituximab era, revealing poor event-free survival but moderate overall survival and high relapse rates, gui

Sep 30, 2026
Critical Care

Septic Shock in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: Outcomes, Prognostic Factors, and Clinical Implications from a Multicenter ICU Cohort

Septic shock following allogeneic hematopoietic stem-cell transplantation has a high 90-day mortality rate of 63%, strongly influenced by illness severity, fungal infection, and neutropenia. Early aminoglycoside use shows complex associatio

Sep 2, 2026Sign in to read
news

Tumor Size as a Prognostic Marker in Thymic Epithelial Tumors: Insights from a Large European Cohort

An analysis of 2,556 thymic tumor cases highlights tumor size as a significant predictor of survival outcomes across thymoma, thymic carcinoma, and neuroendocrine thymic tumors.

Aug 27, 2026
Neurology

Reevaluating Age as a Prognostic Marker in Molecularly Defined Lower-Grade Gliomas

This article examines how age, traditionally considered a high-risk factor in lower-grade gliomas, influences prognosis and treatment decisions in the molecular era, highlighting the importance of IDH mutation status.

Aug 13, 2026
news

Which Patients with Open-Angle Glaucoma Progress Faster? Key Prognostic Factors from a Cochrane Synthesis

A Cochrane review of 22 cohort studies (6,082 patients) found bilateral disease, disc haemorrhage, female sex, and active treatment have the most consistent associations with visual-field progression in open-angle glaucoma, but overall evid

Dec 15, 2025
Clinical Updates

Long-Term Survival Following Cytoreductive Surgery and HIPEC for Pseudomyxoma Peritonei: Insights from a 22-Year Single Institution Experience and Contemporary Evidence Synthesis

22-year single-center data confirm CRS and HIPEC as safe, effective for PMP, yielding 62% 5-year survival. Prognostic factors, optimized HIPEC regimens, and perioperative management impact outcomes and recurrence.

Nov 6, 2025Sign in to read
news

Pre-Fitting Predictors of 2‑Year Hearing Aid Use in 284,175 US Veterans: When Patient Context Matters More Than Audiometry

In 284,175 US veterans, nonmodifiable pre‑fitting factors—health comorbidity, mental status, prior hearing‑aid experience, age, race/ethnicity, and partnership—were independently associated with 2‑year hearing‑aid use persistence, beyond au

Nov 4, 2025
Gastroenterology

Persistent High Mortality in Severe Alcohol-Associated Hepatitis: Insights from a Five-Decade Meta-Analysis

This meta-analysis reveals that short-term mortality in severe alcohol-associated hepatitis remains high, with no significant improvement over the past four decades despite advances in care, underscoring the urgent need for better therapies

Oct 9, 2025

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