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MedXY AI/MedXY News/Tag: Epigenetics
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Epigenetics

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Unveiling PUS7’s Role in Pulmonary Hypertension: A Novel Epigenetic Driver of Vascular Remodeling
CardiologyHuyết Áp PhổiPseudouridylation

Unveiling PUS7’s Role in Pulmonary Hypertension: A Novel Epigenetic Driver of Vascular Remodeling

By MedXY|Sep 5, 2026

This article explores how PUS7-induced pseudouridylation of TGFBI mRNA promotes pulmonary hypertension via epigenetic regulation, revealing promising new therapeutic targets.

Enhancing Prognostic Accuracy in Acute Myeloid Leukemia through DNA Methylation Signatures
Hematology-OncologyDNA methylationprognostic markers

Enhancing Prognostic Accuracy in Acute Myeloid Leukemia through DNA Methylation Signatures

By MedXY|Aug 28, 2026

DNA methylation profiling in AML patients reveals epigenetic subtypes that mirror genetic mutations, improving risk stratification and outcome prediction beyond standard genetic markers.

Epigenetic Silencing of Hepatocyte FoxO1: A Novel Mechanism Disrupting Liver Immune Balance and Driving Inflammation
GastroenterologyFoxO1Immunoregulation

Epigenetic Silencing of Hepatocyte FoxO1: A Novel Mechanism Disrupting Liver Immune Balance and Driving Inflammation

By MedXY|Aug 18, 2026

Epigenetic repression of hepatocyte FoxO1 disrupts immune homeostasis in the liver, promoting inflammation via altered NKT cell regulation, revealing promising therapeutic targets for inflammatory liver diseases.

Blood-Based DNA Methylation Models May Improve Cardiovascular Risk Prediction in Type 2 Diabetes
CardiologyDNA methylationcardiovascular risk

Blood-Based DNA Methylation Models May Improve Cardiovascular Risk Prediction in Type 2 Diabetes

By MedXY|Jul 25, 2026

A study of 305 individuals with type 2 diabetes found that blood-based DNA methylation models predicted 5-year major adverse cardiovascular events with high accuracy, suggesting potential for improved risk stratification.

Blood DNA Methylation Maps Atherosclerosis Across Vascular Beds: Strong Signals, but Mostly a Record of Cumulative Risk Exposure
CardiologyatherosclerosisDNA methylation

Blood DNA Methylation Maps Atherosclerosis Across Vascular Beds: Strong Signals, but Mostly a Record of Cumulative Risk Exposure

By MedXY|Jun 19, 2026

In 2 prospective cohorts, blood DNA methylation was associated with carotid, coronary, and peripheral atherosclerosis, but most signals overlapped with smoking and cardiometabolic risk factors rather than vessel-specific biology.

Beyond the Wrinkles: Unveiling 3 Hidden Accelerators of Aging After 50
Family Medicine & NutritionagingEpigenetics

Beyond the Wrinkles: Unveiling 3 Hidden Accelerators of Aging After 50

By MedXY|Oct 7, 2025

Stanford scientists identify smoking, cadmium, and lead as major environmental factors accelerating biological aging, revealing new insights into how lifestyle and environment shape health beyond genetics.

Exploring the Therapeutic Potential of Betaine and Its Derivatives in Cancer Treatment: From Mechanisms to Clinical Implications
Family Medicine & Nutritionantioxidantscancer therapy

Exploring the Therapeutic Potential of Betaine and Its Derivatives in Cancer Treatment: From Mechanisms to Clinical Implications

By MedXY|Oct 5, 2025

Betaine, a natural methyl donor with antioxidant and anti-inflammatory properties, demonstrates promising anticancer activity across multiple cancer types. Its derivatives and nanotechnology-assisted delivery systems enhance therapeutic eff

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