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Subclinical Vascular Burden Predicts 20‑Year Cognitive Decline: Arteriosclerosis and Atherosclerosis Outperform Blood Pressure and Cardiac Measures

MedXY Editorial Team•Nov 5, 2025•Cardiology
atherosclerosiscognitive decline

Highlights

• In the Multi‑Ethnic Study of Atherosclerosis (MESA), baseline composite measures of arteriosclerosis and atherosclerosis were more consistently associated with cognitive decline and incident cognitive impairment (MCI/dementia) over 20 years than composites of blood pressure or cardiac function.

• Associations were observed across cognitive domains and racial/ethnic subgroups and persisted after accounting for clinical dementia risk factors.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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