Medication Adherence in Hypertension: Insights from the TEAMLET Cluster Randomized Clinical Trial and Related Advances

MedXY Editorial Team•Oct 7, 2025•Cardiology

Medication adherence remains a critical but underrecognized challenge in hypertension management, affecting approximately half of patients.
The TEAMLET pragmatic cluster RCT employed linked electronic health record and pharmacy data combined with team-based care but did not improve adherence or blood pressure control compared to usual care.
Pharmacist-led digital health interventions and theory-based behavioral strategies show promise in improving adherence, emphasizing personalization and patient engagement.
Procedural approaches, such as renal denervation, offer adherence-independent alternatives but necessitate appropriate patient selection and optimization of medical therapy.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

Medication adherence remains a critical but underrecognized challenge in hypertension management, affecting approximately half of patients.
The TEAMLET pragmatic cluster RCT employed linked electronic health record and pharmacy data combined with team-based care but did not improve adherence or blood pressure control compared to usual care.
Pharmacist-led digital health interventions and theory-based behavioral strategies show promise in improving adherence, emphasizing personalization and patient engagement.
Procedural approaches, such as renal denervation, offer adherence-independent alternatives but necessitate appropriate patient selection and optimization of medical therapy.