Seventeen Years On: Robust Population-Level Effectiveness and Herd Protection from HPV Vaccination in High-Risk Young Women

Highlight

Four main points emerge from the study: (1) The introduction of HPV vaccines over 17 years has led to marked reductions in vaccine-type HPV infections among vaccinated young women. (2) Herd protection effects are evident, with decreases in HPV infection also noted in unvaccinated women. (3) These benefits persist despite participants being sexually experienced and at increased risk for HPV infection. (4) Population-level data affirm the real-world impact of both the 2-valent, 4-valent, and 9-valent vaccines across time.

Study Background and Disease Burden