Higher Mortality When Children on Mechanical Ventilation Are Cared for Outside ICUs: National Japanese Cohort Signals Need for Pediatric ICU Centralization
Highlights
– In a national Japanese inpatient database spanning July 2010–March 2022, 129,375 children (≤14 years) received invasive mechanical ventilation; 63% were cared for in general wards rather than ICUs.
– After 1:1 propensity score matching (15,760 pairs), in-hospital mortality was higher for children treated on general wards compared with ICUs (6.4% vs. 4.1%; OR 1.49; 95% CI 1.35–1.65; p < 0.001).
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