High-Dose Vitamin C After Cardiac Arrest: Promise Meets a Negative Signal in VITaCCA
Highlights
Early intravenous vitamin C, given for 96 hours after shockable out-of-hospital cardiac arrest, did not reduce post-cardiac arrest organ dysfunction.
The highest dose tested, 10 g daily, was associated with less improvement in the R-SOFA score and signals of worse troponin release, renal function, and neurological outcomes.
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