Traditional lesion-based analysis often fails to fully predict cerebral palsy (CP) outcomes; lesion network mapping (LNM) provides a more comprehensive predictive framework.
The development of CP following neonatal arterial ischemic stroke is significantly associated with functional disruptions in regions far beyond the primary motor cortex.
Key extramotor regions identified in the CP-related network include the thalamus, basal ganglia, cerebellum, and the insula.
Integrating routine clinical imaging with normative large-scale connectome data from the Developing Human Connectome Project enhances prognostic accuracy.
Introduction: The Clinical Challenge of Neonatal Stroke
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
