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Foundation Models Narrow the Knowledge Gap in Ophthalmology but Struggle with Images

MedXY Editorial Team•Nov 25, 2025•AI
ophthalmology

Highlight

• In a cross-sectional evaluation of offline FRCOphth Part 2 preparation questions, seven foundation models (FMs) showed strong performance on textual multiple-choice items; the best-performing FM (Claude 3.5 Sonnet) achieved 77.7% accuracy, comparable with expert ophthalmologists.

• Multimodal performance (questions that included images or other non-text inputs) remained substantially lower: the top multimodal FM (GPT-4o) scored 57.5%, underperforming expert clinicians and trainees.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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