Dolutegravir and Metabolic Health in Children: Five-Year Insights from the ODYSSEY Trial
Highlights
- Dolutegravir-based ART shows no evidence of excessive weight gain or increased adiposity compared to efavirenz or protease inhibitor-based regimens in children and adolescents over a five-year period.
- Metabolic health parameters, including total cholesterol, triglycerides, and glucose levels, were significantly more favorable in participants receiving dolutegravir.
- Findings provide robust evidence supporting the World Health Organization recommendation of dolutegravir as the preferred antiretroviral for pediatric populations.
Background: Addressing the Weight Gain Concern in Pediatric HIV
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.