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Dolutegravir and Metabolic Health in Children: Five-Year Insights from the ODYSSEY Trial
newsdolutegravirmetabolic health

Dolutegravir and Metabolic Health in Children: Five-Year Insights from the ODYSSEY Trial

By MedXY|Feb 14, 2026

Ancillary analysis of the ODYSSEY trial demonstrates that dolutegravir-based ART is not associated with excessive weight gain or adiposity in children and adolescents compared to standard care, while offering a superior metabolic profile ov

Very Early Neonatal ART Enables ART‑Free HIV‑1 Remission in Some Children: Clinical Insights from IMPAACT P1115
HIV/AIDSpediatric HIV

Very Early Neonatal ART Enables ART‑Free HIV‑1 Remission in Some Children: Clinical Insights from IMPAACT P1115

By MedXY|Nov 12, 2025

IMPAACT P1115 shows that initiating combination ART within 48 hours of birth can enable sustained ART‑free HIV‑1 remission for 48+ weeks in a subset of children with in‑utero infection, but careful selection, close monitoring and standardiz

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