Calcitonin Doubling Rate Sharpens Postoperative Recurrence Risk Stratification in Medullary Thyroid Carcinoma With Biochemical Persistent Disease

Proposed article structure

This topic is best organized around the clinical problem of biochemical persistence after surgery for medullary thyroid carcinoma, the rationale for dynamic biomarker kinetics, the retrospective cohort design, the main prognostic findings, and the implications for surveillance and risk-adapted follow-up. A clinically useful structure is: Highlights; Background and unmet need; Study design and methods; Key results; Clinical interpretation and expert commentary; Practice implications; Limitations; Conclusion; Funding and trial registration; References.

Highlights