Aspirin in the Healthy Elderly: ASPREE’s Clear Message — No Benefit, Higher Bleeding, and Unexpected Cancer Signal
Highlights
Aspirin did not prolong disability‑free survival in healthy older adults and produced no meaningful reduction in cardiovascular events. Major hemorrhage was significantly more frequent with aspirin (HR ~1.38 in-trial). An unexpected increase in all‑cause and cancer‑related mortality was observed during the randomized phase; extended follow‑up showed no long‑term cardiovascular benefit and persistently higher bleeding.
Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.