Adjunctive Ultrasonography Reduces Advanced Breast Cancer Risk in Women Aged 40-49: Long-Term Evidence from J-START
Highlights
– Adjunctive ultrasonography (US) combined with mammography (MG) reduced the cumulative incidence of advanced breast cancer (Stage 2 or higher) by 17% compared to MG alone (HR 0.83, p=0.026).
– The divergence in advanced cancer incidence between the two groups became significant after 48 months, suggesting a long-term benefit from early detection.
– This study provides robust evidence for the integration of US into screening programs for women aged 40-49, particularly in Asian populations where dense breast tissue is common.
Introduction: Addressing the Screening Gap in Younger Women
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.