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Impact of Population-Based Pathogenic Variant Testing on Risk-Based Breast Screening Recommendations
newsbreast cancer screeningpathogenic variants

Impact of Population-Based Pathogenic Variant Testing on Risk-Based Breast Screening Recommendations

By MedXY|Jun 10, 2026

Population-based testing for breast cancer pathogenic variants identified many women who would not have been flagged by clinical or polygenic risk models, supporting its role in risk-based screening.

AI-Supported Mammography Outperforms Standard Double Reading: Insights from the MASAI Trial
AIartificial intelligencebreast cancer screening

AI-Supported Mammography Outperforms Standard Double Reading: Insights from the MASAI Trial

By MedXY|Mar 2, 2026

The MASAI trial demonstrates that AI-supported mammography screening achieves higher sensitivity and non-inferior interval cancer rates compared to standard double reading, while maintaining specificity and significantly reducing radiologis

Long-term Impact of Adjunctive Ultrasonography on Advanced Breast Cancer: A Secondary Analysis of the J-START Trial
Clinical Updatesbreast cancer screeningUltrasonography

Long-term Impact of Adjunctive Ultrasonography on Advanced Breast Cancer: A Secondary Analysis of the J-START Trial

By MedXY|Feb 25, 2026

This review analyzes the J-START trial’s secondary findings, demonstrating that adjunctive ultrasonography significantly reduces the 11-year cumulative incidence of advanced breast cancer in women aged 40–49, particularly those with d

Adjunctive Ultrasonography Reduces Advanced Breast Cancer Risk in Women Aged 40-49: Long-Term Evidence from J-START
newsbreast cancer screeningoncology

Adjunctive Ultrasonography Reduces Advanced Breast Cancer Risk in Women Aged 40-49: Long-Term Evidence from J-START

By MedXY|Mar 2, 2026

A prespecified secondary analysis of the J-START trial reveals that adding ultrasonography to mammography for women aged 40-49 significantly reduces the long-term cumulative incidence of advanced breast cancer, particularly in populations w

Moving Beyond Birthdays: Five-Year Absolute Risk-Based Screening Outperforms Age-Based Mammography
newsbreast cancer screeningmammography

Moving Beyond Birthdays: Five-Year Absolute Risk-Based Screening Outperforms Age-Based Mammography

By MedXY|Feb 9, 2026

A CISNET modeling study demonstrates that mammography screening tailored to 5-year absolute invasive breast cancer risk reduces false-positive recalls by up to 23% while maintaining or improving mortality benefits compared to traditional ag

Personalizing Breast Cancer Screening: Insights from the WISDOM Trial on Risk-Based vs Annual Mammography
newsbreast cancer screeninggenetics

Personalizing Breast Cancer Screening: Insights from the WISDOM Trial on Risk-Based vs Annual Mammography

By MedXY|Dec 17, 2025

The WISDOM trial shows risk-based breast cancer screening using genetic and clinical data as a safe alternative to annual mammography, tailoring screening frequency by individual risk without increasing advanced cancer rates.

Boosting Mammogram Screening Rates: What Really Works for Overdue Women?
newsbehavioral interventionbreast cancer screening

Boosting Mammogram Screening Rates: What Really Works for Overdue Women?

By MedXY|Nov 18, 2025

A Singapore trial shows simple mailed reminders effectively increase overdue mammogram screenings; additional incentives or digital interventions offer no significant benefit.

Removing Out-of-Pocket Costs Increases Access to 3D Mammograms
newsbreast cancerbreast cancer screening

Removing Out-of-Pocket Costs Increases Access to 3D Mammograms

By MedXY|Sep 30, 2025

Eliminating a $45 fee for advanced breast cancer screening technology improves access and reduces health disparities, according to recent research.

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