40‑Hz Light During Sleep Evokes Gamma Activity Without Disrupting Sleep: A Feasibility Step Toward Noninvasive Dementia Therapies
Highlights
– 40‑Hz visual stimulation (VS) delivered during NREM and REM sleep produces frequency‑specific gamma-band EEG responses (SSVEP) comparable across sleep stages and wakefulness.
– In 30 healthy participants, nocturnal 40‑Hz VS increased 40‑Hz spectral power without objectively or subjectively degrading sleep beyond first‑night effects.
– Findings support feasibility for nocturnal gamma entrainment as a scalable experimental tool and a candidate noninvasive intervention for dementia, while highlighting the need for longer, disease‑targeted trials.
Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.