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MedXY AI/MedXY News/Tag: Sarcopenia
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Rapid Skeletal Muscle Loss in Cirrhosis: Predictors, Outcomes, and Implications for Clinical Management
GastroenterologycirrhosisSarcopenia

Rapid Skeletal Muscle Loss in Cirrhosis: Predictors, Outcomes, and Implications for Clinical Management

By MedXY|Aug 4, 2026

Rapid skeletal muscle loss occurs in a significant subset of cirrhosis patients and independently predicts waitlist mortality, highlighting sarcopenia as a critical therapeutic target in liver disease management.

Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank
Neurologygrip strength
Sarcopenia

Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank

By MedXY|May 10, 2026

In nearly 483,000 UK Biobank participants, sarcopenia, low grip strength, and slow walking pace were associated with higher risks of incident stroke and poorer survival after stroke.

Gut-Muscle Axis: Roseburia inulinivorans as a Novel Mediator of Skeletal Muscle Strength and Fiber-Type Composition
Clinical Updatesgut microbiotamuscle strength

Gut-Muscle Axis: Roseburia inulinivorans as a Novel Mediator of Skeletal Muscle Strength and Fiber-Type Composition

By MedXY|Mar 11, 2026

This clinical update synthesizes evidence on Roseburia inulinivorans, identifying it as a species-specific gut microbe that enhances muscle strength by modulating amino acid metabolism and skeletal muscle fiber types.

AI-Derived Sarcopenia Metrics Predict Survival Benefit from Anti-EGFR Therapy in RAS Wild-Type Metastatic Colorectal Cancer
AIartificial intelligencemetastatic colorectal cancer

AI-Derived Sarcopenia Metrics Predict Survival Benefit from Anti-EGFR Therapy in RAS Wild-Type Metastatic Colorectal Cancer

By MedXY|Jan 8, 2026

A deep learning analysis of the PanaMa trial reveals that the benefit of adding panitumumab to maintenance therapy for RAS wild-type mCRC is significantly higher in patients with a high muscle-bone ratio, suggesting a new AI-driven approach

Muscle-Bone Ratio: A New AI-Driven Biomarker for Anti-EGFR Response in Metastatic Colorectal Cancer
AIdeep learningmCRC

Muscle-Bone Ratio: A New AI-Driven Biomarker for Anti-EGFR Response in Metastatic Colorectal Cancer

By MedXY|Jan 8, 2026

A deep learning-derived sarcopenia marker, the muscle-bone ratio (MBR), has been shown to predict the efficacy of anti-EGFR maintenance therapy in patients with RAS wild-type metastatic colorectal cancer, potentially identifying those who t

Why Our Strength and Fitness Peak in Our 20s–30s — and How Exercise Can Push Back the Clock
Internal Medicineagingexercise

Why Our Strength and Fitness Peak in Our 20s–30s — and How Exercise Can Push Back the Clock

By MedXY|Dec 20, 2025

A 47-year study shows physical capacity peaks in the late 20s–30s and accelerates downward from about age 40 — but regular exercise, started at any age, can meaningfully delay decline.

Baseline Sarcopenia Predicts Faster Knee Osteoarthritis Progression and Much Higher Risk of Knee Replacement
newsknee osteoarthritisKnee Replacement

Baseline Sarcopenia Predicts Faster Knee Osteoarthritis Progression and Much Higher Risk of Knee Replacement

By MedXY|Nov 1, 2025

In a longitudinal analysis of 4,316 Osteoarthritis Initiative participants, baseline sarcopenia screened by SARC-F and chair-stand testing was associated with accelerated radiographic and symptomatic knee OA progression over 24–48 months an

Prehabilitation in Sarcopenic Patients Undergoing Major Hepatectomy: Evidence from the PREHEP Trial
Gastroenterologyexercise therapyMajor Hepatectomy

Prehabilitation in Sarcopenic Patients Undergoing Major Hepatectomy: Evidence from the PREHEP Trial

By MedXY|Oct 10, 2025

A 6-week multimodal prehabilitation program combining exercise and nutrition significantly reduces postoperative morbidity in sarcopenic patients undergoing major liver resection, highlighting a promising strategy to improve surgical outcom

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