Prehabilitation in Sarcopenic Patients Undergoing Major Hepatectomy: Evidence from the PREHEP Trial
exercise therapyMajor HepatectomyNutritional SupportPostoperative MorbidityPrehabilitationSarcopenia
Highlight
- Prehabilitation combining structured physical exercise and nutritional supplementation significantly reduces 90-day postoperative morbidity after major hepatectomy in sarcopenic patients.
- The PREHEP randomized clinical trial demonstrated an absolute risk reduction of 36.7% in overall complications and eliminated major complications in the prehabilitation group.
- Muscle mass and strength improved significantly only in patients receiving the multimodal prehabilitation program, underscoring the importance of targeted interventions for sarcopenia.
Study Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.