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Real-World Five-Year Survival After Neoadjuvant Therapy and Surgery in Localized Pancreatic Ductal Adenocarcinoma
General Surgeryrecurrencefive-year survival

Real-World Five-Year Survival After Neoadjuvant Therapy and Surgery in Localized Pancreatic Ductal Adenocarcinoma

By MedXY|Sep 15, 2026

This study reveals that over one-third of patients with localized PDAC receiving neoadjuvant therapy and surgery achieve actual five-year survival, highlighting the impact of early systemic failure and identifying factors predicting long-te

Incidence, Survival, and Symptomatology of Recurrence in Vulvar Cancer: Insights from Population-Based Cohort Studies and Contemporary Evidence
Clinical Updatessymptoms
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survival

Incidence, Survival, and Symptomatology of Recurrence in Vulvar Cancer: Insights from Population-Based Cohort Studies and Contemporary Evidence

By MedXY|Sep 12, 2026

Vulvar cancer exhibits significant recurrence rates, predominantly local, with survival declining sharply after recurrence. Awareness of recurrence-associated symptoms enhances early detection. Surgery remains pivotal in management, with fr

Evaluating Quality of Life and Recurrence in Recurrent Diverticulitis: A Prospective Multicenter Study Comparing Colectomy and Observation
GastroenterologyrecurrenceNghiên cứu quan sát

Evaluating Quality of Life and Recurrence in Recurrent Diverticulitis: A Prospective Multicenter Study Comparing Colectomy and Observation

By MedXY|Sep 8, 2026

This multicenter prospective study reveals that colectomy in recurrent sigmoid diverticulitis improves disease-specific quality of life and reduces 1-year recurrence compared to observation, informing surgical decision-making.

Revisiting HER2 Status in Recurrent Cervical Cancer: Clinical Implications of Dynamic Expression for Targeted Therapy
newsrecurrenceHER2

Revisiting HER2 Status in Recurrent Cervical Cancer: Clinical Implications of Dynamic Expression for Targeted Therapy

By MedXY|Aug 18, 2026

HER2 expression in recurrent cervical cancer varies notably by histology and recurrence site, underscoring the importance of reassessment to guide HER2-targeted treatments effectively.

Impact of Surgical Unit Volume on Recurrence and Complications after Open Mesh Groin Hernia Repair: Insights from a Nationwide Swedish Cohort
General SurgeryrecurrenceSurgical Volume

Impact of Surgical Unit Volume on Recurrence and Complications after Open Mesh Groin Hernia Repair: Insights from a Nationwide Swedish Cohort

By MedXY|Aug 11, 2026

A large nationwide Swedish study reveals that surgical unit volume has minimal impact on recurrence rates after elective open anterior mesh groin hernia repair, but low-volume units face higher risks during emergency repairs.

Genomic Profiling of Primary Gastric Tumors Predicts Recurrence Patterns and Survival Outcomes
Gastroenterologytumor genomicsrecurrence

Genomic Profiling of Primary Gastric Tumors Predicts Recurrence Patterns and Survival Outcomes

By MedXY|Aug 9, 2026

Genomic alterations in primary gastric tumors, including KRAS and PIK3CA mutations, correlate with recurrence risk and metastatic patterns, informing personalized postoperative surveillance and treatment strategies.

Resection Margin Status in Distal Cholangiocarcinoma: Implications for Recurrence and Adjuvant Radiotherapy Selection
General SurgeryrecurrenceAdjuvant radiotherapy

Resection Margin Status in Distal Cholangiocarcinoma: Implications for Recurrence and Adjuvant Radiotherapy Selection

By MedXY|Aug 6, 2026

This study elucidates the prognostic importance of bile duct resection margin status in distal cholangiocarcinoma, revealing that margin involvement significantly affects recurrence risk in node-negative patients and identifies potential ca

Machine Learning Clustering Reveals Distinct Phenotypes in Bilateral Hepatocellular Carcinoma
Gastroenterologybilateral hepatocellular carcinomahepatectomy

Machine Learning Clustering Reveals Distinct Phenotypes in Bilateral Hepatocellular Carcinoma

By MedXY|Jun 4, 2026

Machine learning identified two distinct bilateral hepatocellular carcinoma phenotypes with different tumor burdens, surgical approaches, and outcomes, suggesting preoperative risk stratification may improve patient selection and treatment

Onlay Mesh Was Linked to Lower Reoperation and Bowel Obstruction Risk Than Retromuscular or IPOM Repair in Primary Ventral Hernia Surgery
General Surgerybowel obstructionmesh placement

Onlay Mesh Was Linked to Lower Reoperation and Bowel Obstruction Risk Than Retromuscular or IPOM Repair in Primary Ventral Hernia Surgery

By MedXY|Jun 1, 2026

A nationwide Danish cohort found lower risks of reoperation for recurrence and bowel obstruction after onlay mesh placement compared with retromuscular repair and IPOM in elective primary ventral hernia repair.

Delayed Surgery in Bowel Obstruction: A Hidden Driver of Mortality and Recurrence in France
GastroenterologyAdhesive small bowel obstructionlaparoscopic surgery

Delayed Surgery in Bowel Obstruction: A Hidden Driver of Mortality and Recurrence in France

By MedXY|Apr 14, 2026

A nationwide French study reveals that surgical delay beyond 9 days triples early mortality risk compared to immediate surgery. While non-operative management carries higher long-term recurrence, timely laparoscopic intervention offers the

Most Women Have Anterior-Apical Prolapse, But Phenotype Does Not Predict Recurrence After Native Tissue Repair
newsApical prolapse surgeryNative tissue repair

Most Women Have Anterior-Apical Prolapse, But Phenotype Does Not Predict Recurrence After Native Tissue Repair

By MedXY|Apr 14, 2026

A combined analysis of 704 women found that anterior-predominant and apical prolapse is the most common phenotype (67.2%) in women undergoing native tissue apical surgery. While symptomatic recurrence ranged from 0% to 29% across phenotype

Perioperative Nivolumab Combined with Irreversible Electroporation Shows Antitumoral Effect in High-Risk BCLC A Hepatocellular Carcinoma: Results from the NIVOLEP Phase 2 Trial
Gastroenterologyablation therapyhepatocellular carcinoma

Perioperative Nivolumab Combined with Irreversible Electroporation Shows Antitumoral Effect in High-Risk BCLC A Hepatocellular Carcinoma: Results from the NIVOLEP Phase 2 Trial

By MedXY|Apr 14, 2026

The NIVOLEP phase 2 trial demonstrates that perioperative nivolumab (neoadjuvant and adjuvant) combined with irreversible electroporation achieves 70.6% one-year local recurrence-free survival in BCLC A HCC patients with high recurrence ris

Immunotherapy Shows Consistent Efficacy in Recurrent Gynecologic Cancers Regardless of Prior Radiation Field Location
newscervical cancerEndometrial Cancer

Immunotherapy Shows Consistent Efficacy in Recurrent Gynecologic Cancers Regardless of Prior Radiation Field Location

By MedXY|Apr 6, 2026

This retrospective study challenges the assumption that prior radiation limits immunotherapy effectiveness in recurrent endometrial and cervical cancers, finding no significant difference in response rates or survival outcomes based on recu

Continued versus Discontinued Oral Anticoagulant Therapy for Unprovoked Venous Thromboembolism: A Target Trial Emulation and Evidence Synthesis
Cardiologybleedingclinical outcomes

Continued versus Discontinued Oral Anticoagulant Therapy for Unprovoked Venous Thromboembolism: A Target Trial Emulation and Evidence Synthesis

By MedXY|Nov 22, 2025

Continued oral anticoagulant therapy after ≥90 days for unprovoked VTE significantly lowers recurrence and mortality despite increased bleeding risk, offering a net clinical benefit consistent across anticoagulant types and treatment durati

Optimizing Mesh Weight to Reduce Recurrence Reoperations in Laparoscopic Inguinal Hernia Repair
General Surgeryrecurrence

Optimizing Mesh Weight to Reduce Recurrence Reoperations in Laparoscopic Inguinal Hernia Repair

By MedXY|Oct 15, 2025

A Danish cohort study identifies that using mesh weighing 45-65 g/m² in laparoscopic inguinal hernia repair results in the lowest reoperation rate for recurrence, guiding surgical mesh selection for better patient outcomes.

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