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This review synthesizes evidence from a large US network study on patient-reported postoperative dental pain, medication use, and functional interference, highlighting procedure-specific pain trajectories and opioid stewardship implications
A randomized trial found that preoperative analgesic education did not significantly reduce opioid consumption or improve pain scores and satisfaction after surgery, highlighting the need for more intensive interventions.
This study associates adjunctive suzetrigine use with decreased postoperative opioid consumption in patients undergoing head and neck free flap or transoral robotic surgery, without increasing pain scores or adverse events.
A recent randomized controlled trial demonstrates that nonopioid analgesia is noninferior to routine opioid prescribing for pain control after minimally invasive hysterectomy, with high patient satisfaction and markedly reduced opioid use.
A systematic review and meta-analysis of 18 RCTs found that acupoint stimulation reduces postoperative pain scores after Cesarean delivery by small but statistically significant amounts across 48 hours, with moderate-to-high certainty evidence.
A retrospective cohort study of 80 patients undergoing tonsillectomy, adenoidectomy, or uvulopalatopharyngoplasty found that adding celecoxib to multimodal analgesia reduced mean opioid consumption by 44%, while maintaining comparable pain
A randomized clinical trial demonstrates that while CYP2D6 genotyping significantly shifts opioid prescribing patterns for poor and intermediate metabolizers, it does not improve pain control or reduce opioid consumption within the context
Preoperative Quercetin significantly reduces post-cesarean pain and accelerates patient mobilization, offering a safe adjunct to current pain management protocols.
