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Portal Hypertension

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Gastroenterology

From Pressure Metrics to Personalized Prognosis: Transforming Risk Assessment in Advanced Chronic Liver Disease

A shift from static portal pressure thresholds to dynamic, non-invasive risk prediction models offers improved prognostic accuracy for decompensation in advanced chronic liver disease, enabling personalized patient management and better cli

Aug 31, 2026
Cardiology

Comparative Effectiveness of Carvedilol Versus Other Nonselective β-Blockers in Cirrhosis: A Clinical Review

Carvedilol demonstrates superior effectiveness over nadolol and propranolol in reducing portal hypertension and preventing cirrhosis decompensation events, with emerging evidence supporting its preferential use in both compensated and decom

Aug 24, 2026Sign in to read
Gastroenterology

Portal Tryptophan Depletion Drives Hyper-Reactive Neutrophils in Alcoholic Liver Disease: Insights from a Prospective TIPS Study

A prospective study reveals that decreased tryptophan levels in portal circulation induce neutrophil hyperactivation in alcoholic liver disease. In vitro supplementation with tryptophan ameliorated neutrophil activation, identifying the gut

Apr 14, 2026
Gastroenterology

Rivaroxaban in Cirrhosis: A Promising Strategy to Prevent Portal Hypertension Complications

The CIRROXABAN trial evaluates rivaroxaban’s efficacy and safety in preventing complications of portal hypertension in cirrhotic patients, suggesting improved complication-free survival without significantly increasing major bleeding

Oct 28, 2025Sign in to read
Gastroenterology

Rivaroxaban in Cirrhosis: A Promising Strategy to Prevent Portal Hypertension Complications

The CIRROXABAN trial evaluates rivaroxaban’s efficacy and safety in preventing complications of portal hypertension in cirrhotic patients, suggesting improved complication-free survival without significantly increasing major bleeding

Oct 28, 2025

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