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The PELICAN trial found that individualized cardiac index-guided intraoperative hemodynamic therapy did not reduce major postoperative complications compared to routine care in high-risk major abdominal surgery patients.
This article analyzes perioperative patient-initiated communication in septorhinoplasty, highlighting common concerns and identifying factors linked to increased contact with clinical teams, providing insights to improve patient care qualit
This study investigates the association between continuation of non-full code status during surgery and early postoperative mortality, revealing higher mortality risk that aligns with clinical care decisions rather than missed rescue opport
This study highlights that geriatric vulnerabilities and comorbidities, once considered nonmodifiable, play a dominant role in 30-day readmissions after colorectal surgery in older adults, emphasizing the need for integrated perioperative i
Preoperative cardiac testing in children with very severe OSA had low diagnostic yield and rarely changed management. Risk appeared highest in obese adolescents with AHI >50 events/hour.
The MOPED study of over 6,000 European patients reveals significant international variations in perioperative diabetes management. Findings demonstrate that higher preoperative HbA1c levels and practice inconsistencies are linked to fewer d
A pragmatic multicenter randomized trial found that coach-supported, home-based multimodal prehabilitation before elective noncardiac surgery did not reduce 30-day postoperative disability or in-hospital complications in older adults with f
In BigpAK-2, a multinational randomized trial, a KDIGO-based preventive bundle triggered by tubular stress biomarkers reduced moderate or severe acute kidney injury within 72 hours after major surgery (OR 0.57; NNT 12) without increasing ad
A retrospective MIMIC‑IV cohort presented at AHA 2025 found perioperative metformin exposure in T2DM patients undergoing cardiac surgery associated with markedly lower 30‑, 90‑ and 360‑day mortality. Results are compelling but observational
In high–cardiac-risk veterans after major vascular or general surgery, a liberal postoperative transfusion threshold (Hb <10 g/dL) did not reduce 90‑day death or major ischemic events compared with a restrictive threshold (Hb <7 g/dL)
This comprehensive review explores the EPO2CH trial, which assessed a multi-component care bundle’s effectiveness in reducing surgical site infections after abdominal surgery, highlighting key findings, limitations, and clinical impli
A large randomized trial shows that ivabradine, despite effectively lowering heart rate during surgery, does not reduce myocardial injury after noncardiac surgery, highlighting the complexity of perioperative cardiac risk management.
A recent survey found 39% of elective sports surgery patients used CBD for pain or sleep, with one-third reporting benefit—underscoring the need for more evidence and opioid alternatives.
