Tag
This review synthesizes evidence from the DCCT/EDIC study highlighting the high prevalence and risk factors of obstructive sleep apnea and poor sleep quality in older adults with long-standing type 1 diabetes, emphasizing the clinical and m
A comprehensive UK cohort study shows that GLP-1 receptor agonists do not reduce the incidence of obstructive sleep apnea compared to DPP-4 inhibitors in obese patients with type 2 diabetes.
Expiratory pressure alleviation during CPAP treatment reduces upper airway patency, increases residual apnea severity, and necessitates higher therapeutic pressure in severe OSA patients, without affecting treatment adherence.
This study reveals that intermittent hypoxia activates GLI1 transcription factor in cardiac fibroblasts, driving fibrosis via PKM2-mediated glycolysis, and highlights GLI1 as a promising therapeutic target in OSA-associated cardiac dysfunct
In patients with OSA and elevated blood pressure, comorbid insomnia is linked to a significantly greater blood pressure reduction following short-term CPAP therapy, highlighting the clinical importance of addressing both sleep disorders.
This review synthesizes current evidence on the impact of hypoglossal nerve stimulation (HGNS) on cardiovascular disease incidence in obstructive sleep apnea patients, highlighting potential long-term cardiovascular benefits and mechanistic
A massive cohort study of 11.3 million US veterans reveals that obstructive sleep apnea is an independent risk factor for Parkinson disease, but early treatment with CPAP significantly reduces this risk, particularly in women.
Sleep disturbances and mood disorders profoundly affect people living with HIV. Modafinil emerges as a promising therapy addressing daytime sleepiness, depression, and cognitive challenges, improving quality of life.
