Tag
A randomized trial demonstrates that adding the digital therapeutic glucura to intermittent CGM and standard care significantly improves HbA1c, weight loss, and mental health in non-insulin-treated type 2 diabetes patients over six months.
This study identifies baseline plasma metabolites, specifically 2hr plasma glucose and ceramide C18:0/C18:1 ratio, as predictors of persistent prediabetes vs. normoglycemia following lifestyle intervention over 5 years.
The LIMS study demonstrates sustained, modest improvements in MS-related functioning and dietary behavior up to 24 months following a digital multimodal lifestyle intervention, supporting lifestyle interventions as complementary to MS manag
The effectiveness of lifestyle interventions promoting physical activity for diabetes risk reduction varies by prediabetes phenotype, with individuals having impaired fasting glucose showing the least response. Tailored approaches may enhan
This study reveals how genetic risk for diabetic retinopathy can be significantly mitigated by healthy lifestyle choices, emphasizing universal behavioral interventions for prevention.
Concurrent exercise added to a palaeolithic diet improves cardiometabolic fitness and post-exercise clearance of ceramides, enhancing fat oxidation in individuals with type 2 diabetes.
This analysis of the China Rural Hypertension Control Project reveals that intensive blood pressure management chiefly drives cardiovascular risk reduction, with modest contributions from behavioral and metabolic changes, highlighting domai
The POINTER Imaging study found no overall brain biomarker changes from a structured lifestyle intervention, but participants with lower baseline hippocampal volume showed greater cognitive benefit, suggesting imaging may help identify who
Long-term follow-up after two lifestyle trials found that reductions in visceral fat, more than overall weight loss, were linked to sustained cardiometabolic benefits and a lower risk of type 2 diabetes.
A sub-analysis of the FINGER trial reveals that individuals with specific grey matter patterns and lower vascular risk derive the most structural brain benefit from multimodal lifestyle interventions, highlighting the potential for personal
A post-hoc analysis of the Look AHEAD trial demonstrates that NT-proBNP levels can identify patients with type 2 diabetes who benefit most from intensive lifestyle interventions. ILI significantly reduced HFpEF risk in those with elevated o
A groundbreaking study reveals that lifestyle changes improving fat distribution and insulin function can reverse prediabetes without weight loss, significantly cutting type 2 diabetes risk.
Over 21 years, intensive lifestyle changes and metformin significantly reduced type 2 diabetes incidence in at-risk adults, with variable effects based on individual baseline risk factors, highlighting opportunities for precision prevention
This review examines the first phase 3 randomized trial demonstrating that an AI-powered Diabetes Prevention Program lifestyle intervention is noninferior to human coaching in improving weight loss, HbA1c, and physical activity among adults
A large-scale network meta-analysis highlights that combined physical exercise and cognitive training most effectively improve cognition in older adults without impairment, emphasizing tailored lifestyle strategies for dementia prevention.
The LIMB-Q trial demonstrates that intensive lifestyle interventions combining weight management and exercise preserve bone quality in older adults with obesity, despite significant weight loss, highlighting a promising approach for mitigat
A 34-year follow-up of the Da Qing Diabetes Study reveals significantly increased stroke incidence among Chinese adults with newly diagnosed type 2 diabetes and impaired glucose tolerance, highlighting the beneficial impact of lifestyle int
A one-year DASH diet intervention led to sustained suppression of proatherogenic chemokine CXCL4 and fewer major cardiovascular events over six years despite reduced adherence and partial loss of initial benefits in nonobstructive CAD patie
Isometric exercises, a form of static muscle engagement, can lower blood pressure as effectively as some medications, offering a simple, drug-free way to protect your heart and vessels.
A large cohort study reveals that metabolic syndrome significantly raises Parkinson’s disease risk by 39%, with even greater risk in genetically predisposed individuals, highlighting the importance of metabolic health management in PD preve
