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This article reviews the incidence of inadvertent parathyroidectomy during thyroidectomy, identifies key risk factors, and discusses clinical significance and emerging strategies for parathyroid preservation.
A randomized controlled trial demonstrates that PTeye-guided near-infrared autofluorescence significantly improves identification and preservation of parathyroid glands during total thyroidectomy, reducing transient hypoparathyroidism, espe
Iatrogenic hypercalcemia complicates 14% of hypoparathyroidism cases post-total thyroidectomy, linked to low early postoperative parathyroid hormone and early vitamin D initiation. Careful supplementation and monitoring are vital in prevent
Prophylactic thyroidectomy in children with MEN2 mutations shows excellent short-term cancer control but carries notable risk of permanent hypoparathyroidism, especially under age 5, highlighting the need for expert multidisciplinary surgic
A nationwide cohort study highlights that thyroid cancer patients with permanent hypoparathyroidism face significantly elevated risks of kidney stones, renal failure, and major cardiovascular events, necessitating comprehensive long-term fo
A nationwide cohort study reveals that permanent postoperative hypoparathyroidism significantly increases the risk of renal insufficiency, nephrolithiasis, and major adverse cardiac events in thyroid cancer patients, highlighting the need f
This multicenter randomized clinical trial demonstrates that fiber-based near-infrared autofluorescence (NIRAF) enhances intraoperative parathyroid gland identification during thyroidectomy and bilateral parathyroidectomy without increasing
A single parathyroid hormone (PTH) measurement 6 hours after total thyroidectomy can accurately predict the risk of transient and permanent hypoparathyroidism, enabling targeted monitoring and potential reduction in hospital stays.
