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Assessing Age-Related Bias in EQ-5D-5L Quality of Life Measures Among Acute Ischemic Stroke Patients: Insights from the ACT Trial
NeurologyEQ-5D-5LDifferential Item Functioning

Assessing Age-Related Bias in EQ-5D-5L Quality of Life Measures Among Acute Ischemic Stroke Patients: Insights from the ACT Trial

By MedXY|Sep 5, 2026

This study evaluates differential item functioning in the EQ-5D-5L questionnaire among acute ischemic stroke patients, revealing minimal impact of age-related biases on quality of life measurement across sex and treatment groups.

Health-Related Quality of Life Following Risk-Reducing Hysterectomy: Insights from a UK Randomised Vignette Study
newshealth-related quality of lifebilateral salpingo-oophorectomy

Health-Related Quality of Life Following Risk-Reducing Hysterectomy: Insights from a UK Randomised Vignette Study

By MedXY|Aug 18, 2026

This study quantifies health-related quality of life impacts associated with risk-reducing hysterectomy, with and without bilateral salpingo-oophorectomy, to aid counseling and economic evaluation in endometrial cancer prevention.

Clinical Metagenomics in Sepsis: Insights from the DigiSep Randomized Controlled Trial
Critical Careclinical outcomeshealth-related quality of life

Clinical Metagenomics in Sepsis: Insights from the DigiSep Randomized Controlled Trial

By MedXY|Jul 2, 2026

The DigiSep trial assessed the impact of metagenomic next-generation sequencing (mNGS) on sepsis outcomes. While primary endpoint improvement was not significant, secondary analyses revealed benefits in mechanical ventilation duration, shoc

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