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Emerging evidence reveals gut microbiota profiles correlate with disease severity and survival in idiopathic pulmonary fibrosis, highlighting potential microbial biomarkers and treatment modifiers.
Genetic susceptibility to metabolic dysfunction-associated steatotic liver disease (MASLD) is amplified by gut microbiota interactions, with ceramides playing a key role; targeted microbial interventions can reverse hepatic injury in at-ris
Recent research identifies intestinal serotonin 5-HT3a receptor signaling via vagal neurons as a key mediator of microbiota-induced hypertension, offering new insights into resistant hypertension and potential therapeutic targets.
Distinct gut microbial profiles but shared metabolomic markers, especially fecal acetate, predict response and survival with combination immunotherapy in metabolic dysfunction-associated and viral hepatitis-related hepatocellular carcinoma.
Emerging evidence identifies circulating imidazole propionate, a gut microbiota-derived metabolite, as an independent predictor of major adverse cardiovascular events in patients with coronary artery disease, offering novel insights into pe
This study reveals that bisphenol F exposure aggravates cardiomyopathy under hemodynamic stress through gut microbiota metabolism, highlighting a novel gut-heart axis involving N-acetylputrescine and potential therapeutic targets.
This clinical update synthesizes evidence on Roseburia inulinivorans, identifying it as a species-specific gut microbe that enhances muscle strength by modulating amino acid metabolism and skeletal muscle fiber types.
Researchers have discovered that Zhenqi Fuzheng Granule enhances PD-1 antibody efficacy in colorectal cancer by modulating the gut microbiota-SCFA-GPR109A axis, effectively suppressing tumor glycolysis and reversing immune exhaustion within
This review explores how gut microbiota disturbances, especially L. reuteri and its metabolite ILA, influence post-TACE liver injury and prognosis in HCC patients, highlighting potential microbiota-targeted therapies.
Altered gut microbiota composition and metabolism exacerbate cirrhotic portal hypertension, highlighting potential microbiome-targeted therapies to mitigate disease progression.
A recent cross-sectional study reveals that alterations in gut microbiota correlate more strongly with impaired health-related quality of life in IBD patients than clinical disease activity, suggesting novel microbial therapeutic targets be
Intratumoral microbiota significantly influence breast cancer development, progression, and therapeutic response. Their diverse composition across subtypes presents diagnostic and prognostic opportunities. Emerging strategies target these m
Recent research reveals distinct gut microbial and metabolic profiles linked to ADHD symptoms, highlighting short-chain fatty acid deficiency as a key mechanism driving hyperactivity and inattention.
A fermentable carbohydrate-enriched diet combined with metformin improves postprandial glycaemia, enhances GLP-1 secretion, and positively alters gut microbiota in prediabetic individuals, offering a personalized nutrition-pharmacology stra
Daily blueberry intake during complementary feeding may enhance allergy symptom resolution, favorably influence immune biomarkers, and promote beneficial gut microbiota shifts in breastfed infants, suggesting new avenues for allergy prevent
Linarin shows promise in mitigating NAFLD by enhancing autophagy via PI3K/Akt/mTOR inhibition, reducing inflammation, and restoring gut microbiota balance, alongside activating the PDE4D/cAMP/PKA/CREB pathway to improve hepatic lipid metabo
Recent research elucidates how smoking modulates gut microbiota and immune responses differently in ulcerative colitis and Crohn’s disease, explaining its protective effect in UC but detrimental role in CD.
Milk small extracellular vesicles select genomic variants in gut bacteria, altering sugar, amino acid, and purine metabolism, impacting microbiota differentiation and host neurodevelopmental outcomes.
The WLM3P weight loss program significantly remodels gut microbiota, enriching beneficial bacteria such as Faecalibacterium, which associates with improved fat and visceral fat loss in adults with obesity compared to standard low-carb diets
A recent Mendelian randomization study suggests bidirectional causal links between specific gut bacteria and insomnia, highlighting potential microbiome-based interventions, though causality remains debated among experts.
