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Antiseizure Medication Use During Pregnancy: Implications for Fetal Growth from the EURAP Registry
NeurologyTăng trưởng thai nhiPregnancy

Antiseizure Medication Use During Pregnancy: Implications for Fetal Growth from the EURAP Registry

By MedXY|Sep 5, 2026

A comprehensive cohort study from the EURAP registry reveals that antiseizure medication, especially polytherapy and certain monotherapies, increases the risk of poor fetal growth, underscoring the need for optimized treatment strategies du

Balancing Risks: Safety Profiles of Antiseizure Medications in Epilepsy Patients on Direct Oral Anticoagulants
Cardiologybleeding riskepilepsy

Balancing Risks: Safety Profiles of Antiseizure Medications in Epilepsy Patients on Direct Oral Anticoagulants

By MedXY|Aug 18, 2026

This study reveals distinct thromboembolic, bleeding, and mortality risks based on antiseizure medication selection in epilepsy patients receiving direct oral anticoagulants, highlighting the critical role of ASM choice on patient safety an

Mapping the Brain’s Eloquence: A Probabilistic Approach to Electrocortical Stimulation in Epilepsy
NeurologyElectrocortical stimulationepilepsy

Mapping the Brain’s Eloquence: A Probabilistic Approach to Electrocortical Stimulation in Epilepsy

By MedXY|Jul 1, 2026

This study develops a comprehensive probabilistic atlas of brain function using extraoperative electrocortical stimulation mapping in epilepsy patients, revealing distributed and variable language and motor cortical organization beyond trad

Neurocognitive Outcomes of In Utero Exposure to Antiseizure Medication: An Australian Cohort Study
Neurologyantiseizure medicationchild development

Neurocognitive Outcomes of In Utero Exposure to Antiseizure Medication: An Australian Cohort Study

By MedXY|Jun 7, 2026

An Australian cohort study found that prenatal exposure to valproate, levetiracetam, topiramate, and carbamazepine was associated with poorer cognitive outcomes in children, while lamotrigine exposure was not.

Rural-Urban Disparities in Epilepsy Outcomes in the United States
NeurologyEEGepilepsy

Rural-Urban Disparities in Epilepsy Outcomes in the United States

By MedXY|Jun 5, 2026

A national U.S. study found that patients with epilepsy from rural counties had worse hospital outcomes, including higher mortality, more status epilepticus, longer stays, and less EEG use, highlighting access-related disparities.

Antiepileptogenesis After Stroke: Assessing the Impact of Eslicarbazepine Acetate on Seizure Prevention
Neurologyclinical trialepilepsy

Antiepileptogenesis After Stroke: Assessing the Impact of Eslicarbazepine Acetate on Seizure Prevention

By MedXY|Mar 6, 2026

This article examines a Phase 2a trial investigating eslicarbazepine acetate for preventing post-stroke epilepsy. While the primary endpoint was not met due to recruitment challenges, the study provides a critical framework for future antie

AI-Driven Prognosis: EEGSurvNet Accurately Predicts Seizure Timing From Routine EEG Data
AIdeep learningEEG

AI-Driven Prognosis: EEGSurvNet Accurately Predicts Seizure Timing From Routine EEG Data

By MedXY|Jan 28, 2026

Researchers developed EEGSurvNet, a deep survival model that analyzes routine EEG to predict seizure risk over two years. Outperforming clinical models, it achieved an AUROC of 0.80 at two months and showed high efficacy in patients without

Impaired Sleep Homeostasis and Respiratory Instability: Identifying Novel Biomarkers for Sudden Unexpected Death in Epilepsy
NeurologyepilepsySUDEP

Impaired Sleep Homeostasis and Respiratory Instability: Identifying Novel Biomarkers for Sudden Unexpected Death in Epilepsy

By MedXY|Dec 23, 2025

This case-control study identifies altered slow-wave activity progression and increased respiratory variability during NREM sleep as significant biomarkers for SUDEP risk, providing a potential framework for objective clinical screening and

Do Behavioural, Self-Management, and Service Delivery Models Improve Outcomes in Adults with Epilepsy?
Neurologybehavioural interventionsepilepsy

Do Behavioural, Self-Management, and Service Delivery Models Improve Outcomes in Adults with Epilepsy?

By MedXY|Dec 17, 2025

A Cochrane review finds limited and low- to moderate-certainty evidence that behavioural, self-management, or service delivery interventions improve seizure control or quality of life in adults with epilepsy.

Limited Evidence for Behavioural and Service Delivery Interventions in Childhood Epilepsy: Urgent Need for Robust Trials
Neurologybehavioural interventionschildren

Limited Evidence for Behavioural and Service Delivery Interventions in Childhood Epilepsy: Urgent Need for Robust Trials

By MedXY|Dec 16, 2025

Current evidence for behavioural and service delivery interventions in childhood epilepsy is scarce and of low quality, highlighting an urgent need for rigorous, long-term trials.

Geographic Clusters of Late-Life Epilepsy in US Medicare: Sleep and Mobility as Key Contextual Drivers
Neurologyepilepsyolder adults

Geographic Clusters of Late-Life Epilepsy in US Medicare: Sleep and Mobility as Key Contextual Drivers

By MedXY|Nov 25, 2025

A Medicare cohort study mapped incident epilepsy among older adults across the contiguous US and linked high-incidence areas to social and environmental determinants—most strongly insufficient sleep and lack of household vehicle access—sugg

Decoding SUDEP: Key Risk Markers and the Role of Peri-Ictal Apnoea in Epilepsy Mortality
NeurologyepilepsySUDEP

Decoding SUDEP: Key Risk Markers and the Role of Peri-Ictal Apnoea in Epilepsy Mortality

By MedXY|Oct 10, 2025

A decade-long prospective study identifies living alone, convulsive seizure frequency, and peri-ictal apnoea as pivotal predictors for sudden unexpected death in epilepsy (SUDEP), highlighting the potential of cardiorespiratory monitoring i

Unraveling the Gut-Brain Axis: Microbiota and Metabolite Shifts Predict Seizure Reduction in Children on the Ketogenic Diet
Diabetes & Endocrinologyepilepsyketogenic diet

Unraveling the Gut-Brain Axis: Microbiota and Metabolite Shifts Predict Seizure Reduction in Children on the Ketogenic Diet

By MedXY|Oct 2, 2025

Serum metabolome and gut microbiota changes during ketogenic diet therapy correlate with seizure reduction in drug-resistant pediatric epilepsy, implicating plasmalogens and specific gut microbes in anti-seizure effects.

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