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This study reveals that distinct gestational diabetes mellitus (GDM) subtypes confer increased risks of prediabetes, diabetes, metabolic syndrome, and cardiovascular disease 10-14 years postpartum, underscoring the need for tailored long-te
This review synthesizes current evidence on menopausal hormone therapy’s cost-effectiveness, highlighting findings from a 2026 Markov model analysis and contextualizing with pivotal studies on health outcomes and economic implications
A large UK cohort study reveals that beta-blockers reduce mortality in COPD patients with heart failure or ischemic heart disease, but concurrent long-acting beta-agonists may attenuate this benefit.
The 2026 ESC clinical consensus outlines creation of multidisciplinary Women’s Heart Centres to close gaps in diagnosis, management, and research for women’s cardiovascular disease across the life course.
This review synthesizes current evidence on the impact of hypoglossal nerve stimulation (HGNS) on cardiovascular disease incidence in obstructive sleep apnea patients, highlighting potential long-term cardiovascular benefits and mechanistic
A comprehensive nationwide study reveals that maternal diabetes during pregnancy, particularly pregestational diabetes, significantly increases offspring’s risk of early-onset cardiovascular diseases, mediated partly by perinatal comp
This review synthesizes evidence that high adolescent cardiorespiratory fitness slightly elevates early adult atrial fibrillation risk but substantially reduces cardiovascular disease incidence later in life, with familial confounders accou
This large-scale study links specific PM2.5 components, especially chloride, black carbon, and sulfate, to increased long-term cardiovascular disease risk, emphasizing targeted pollution control for better heart health.
A large-scale Dutch cohort study reveals that women with a history of spontaneous preterm birth face a significantly elevated risk of cardiovascular mortality, with the highest risk observed in those delivering before 32 weeks of gestation.
Thyroid dysfunction reshapes lipid metabolism, vascular tone, cardiac performance, and rhythm. Cardiovascular risk is clearest at the extremes of thyroid status, while treatment decisions in subclinical disease should remain individualized.
Higher proteinuria in preeclampsia was linked to greater long-term risk of maternal hypertension and chronic kidney disease, with overall increased risk of cardiovascular disease as well.
A nationwide study reveals that eclampsia patients face a 6.9-fold increased risk of cardiovascular disease readmission within the first year postpartum, with stroke risk nearly 13 times higher than normotensive patients. These findings und
This large-scale proteomic analysis identifies 15 novel protein markers for venous thromboembolism, offering new insights into the roles of immunity and extracellular matrix regulation in VTE pathogenesis beyond traditional coagulation path
This article explores the transformation of lipid management through PCSK9 inhibitors. From genetic discovery to landmark cardiovascular outcomes trials, we examine how monoclonal antibodies, RNA interference, and gene editing are redefinin
A comprehensive simulation study evaluates the cost-effectiveness of semaglutide for secondary cardiovascular prevention in US adults without diabetes, finding significant health benefits but highlighting the need for price reductions to en
A longitudinal analysis from the SWAN study indicates that women treated with levothyroxine for hypothyroidism do not face a higher risk of cardiovascular events compared to those without thyroid disease, providing clinical reassurance for
This emulation study applies SELECT trial data to over 600,000 individuals, suggesting that GLP-1RAs could significantly reduce 10-year cardiovascular risk in high-risk obese populations without existing disease, offering a potential 22% re
This review synthesizes findings on how pregnancy biomarkers, particularly sFlt-1 and hs-cTnI, serve as early indicators of long-term maternal cardiovascular risk, offering a unique window for sex-specific prevention.
Recent data from the ARIC study and emerging expert consensus are redefining primary aldosteronism. Rather than a rare, all-or-nothing condition, it is now viewed as a broad spectrum where even subclinical elevations significantly increase
This review synthesizes findings from a 21- **Compiling final edits** Now that I’ve structured the article, I’m focusing on the final touches, particularly the content for the “Highlights,” “Expert Commentary,&
