Adolescent Cardiorespiratory Fitness and the Trade-Off Between Atrial Fibrillation Risk and Cardiovascular Benefits: Evidence from a Nationwide Sibling-Controlled Cohort Study
Highlights
- High cardiorespiratory fitness in adolescence is associated with a small excess risk of atrial fibrillation (AF) during early adulthood.
- This AF risk is outweighed by a substantially larger reduction in non-AF cardiovascular disease (CVD) risk from middle age onward.
- Sibling-controlled analyses reveal that shared familial factors partly explain the observed associations, eliminating any early life cardiovascular disadvantage.
- Findings reinforce public health initiatives promoting improved adolescent fitness for long-term cardiovascular benefits.
Background
MedXY registered readers
Sign in free to continue reading
Create or use your MedXY account to unlock the complete article.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.