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A multicenter randomized trial found that initiating a 1-hour resuscitation bundle including early antibiotics, fluids, vasopressors, and hydrocortisone in the prehospital setting did not significantly reduce 28-day mortality in adults with
A nationwide retrospective cohort (36,129 patients) found antibiotic use before or during biologic treatment for psoriasis was associated with higher risk of discontinuation or switch; multiple dispensations carried larger risk, suggesting
A multicenter study in Japan found that adequate daptomycin dosing significantly improves clinical outcomes in pediatric patients, while adverse events can occur regardless of renal function.
A clinical study reveals that trimethoprim-sulfamethoxazole does not significantly improve infant birth weight or related outcomes in HIV-positive pregnancies.
Research highlights increased birth defect risks linked to TMP-SMX use in pregnancy, urging cautious antibiotic selection for treating UTIs.
Research presented at the European Respiratory Society’s annual meeting links early antibiotic use in children to increased allergy risks such as eczema and hay fever.
Exploring why certain medications start with a larger first dose, the clinical evidence, common misconceptions, and practical guidelines for safe use.
Explore the scientific reasons behind antibiotic-associated diarrhea in children, common misconceptions, and practical advice for parents and clinicians.