Stem Cell Therapy for Avascular Necrosis of the Femoral Head: Promise or Pitfall? A Comprehensive Meta-Analysis

MedXY Editorial TeamOct 12, 2025

Highlight

– Stem cell therapy (SCT) combined with mechanical support or bone grafting shows potential to improve functional outcomes in avascular necrosis of the femoral head (ONFH).
– Pure SCT alone generally fails to demonstrate statistically significant improvements.
– SCT combined with mechanical support may reduce risk of total hip replacement (THR) and improve Harris Hip Score (HHS).
– Evidence certainty is moderate for delaying THR but low for other outcomes due to methodological variability.

Study Background

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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