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Stem Cell Therapy for Complex Perianal Fistulas: Why the ADMIRE CD II Trial Missed Its Mark
GastroenterologyCrohn’s diseasestem cell therapy

Stem Cell Therapy for Complex Perianal Fistulas: Why the ADMIRE CD II Trial Missed Its Mark

By MedXY|Mar 6, 2026

The ADMIRE CD II Phase 3 trial failed to show a significant benefit of darvadstrocel over placebo for complex perianal fistulas in Crohn’s disease, primarily due to an unexpectedly high remission rate in the placebo-controlled surgica

Cellular Therapy for In-Utero Myelomeningocele Repair: Results from the CuRe Phase 1 Trial
newsneurosurgeryregenerative medicine

Cellular Therapy for In-Utero Myelomeningocele Repair: Results from the CuRe Phase 1 Trial

By MedXY|Mar 6, 2026

This phase 1 study evaluates the safety of placenta-derived mesenchymal stem cells (PMSCs) seeded on an extracellular matrix for in-utero repair of myelomeningocele, demonstrating successful surgical outcomes and no cell-related adverse eve

Stem Cell Therapy for Avascular Necrosis of the Femoral Head: Promise or Pitfall? A Comprehensive Meta-Analysis
newsorthopedicsregenerative medicine

Stem Cell Therapy for Avascular Necrosis of the Femoral Head: Promise or Pitfall? A Comprehensive Meta-Analysis

By MedXY|Oct 12, 2025

This meta-analysis evaluates stem cell therapy combined with mechanical support for avascular necrosis of the femoral head, highlighting modest improvements in function and delayed disease progression compared to stem cells alone.

Advancing Type 1 Diabetes Care: Stem Cell-Derived Islet Therapy with Zimislecel
Diabetes & Endocrinology膵島移植stem cell therapy

Advancing Type 1 Diabetes Care: Stem Cell-Derived Islet Therapy with Zimislecel

By MedXY|Oct 7, 2025

Zimislecel, an allogeneic stem cell-derived islet-cell therapy, demonstrates promising safety and efficacy for type 1 diabetes, restoring physiologic islet function and enabling insulin independence in a phase 1-2 trial.

Intrathecal Autologous Bone Marrow Mononuclear Cell Therapy Plus Education: A Promising Approach for Autism Spectrum Disorder?
Clinical Updatesautism spectrum disorderclinical trial

Intrathecal Autologous Bone Marrow Mononuclear Cell Therapy Plus Education: A Promising Approach for Autism Spectrum Disorder?

By MedXY|Oct 2, 2025

A phase II trial finds that intrathecal autologous bone marrow mononuclear cell therapy combined with education significantly improves core symptoms and adaptive behaviors in young children with ASD compared to education alone.

Stem Cell Therapy: A New Frontier in Restoring Fertility for Women with Ovarian Failure
newsfertilitystem cell therapy

Stem Cell Therapy: A New Frontier in Restoring Fertility for Women with Ovarian Failure

By MedXY|Sep 30, 2025

Recent research highlights stem cell therapy as a promising method for improving fertility in women facing ovarian failure, showing significant oocyte activation and pregnancy rates.

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