RBC Transfusions in Early Sepsis Resuscitation: Common, Complex, and Potentially Harmful Above a 10 g/dL Threshold
Highlights
– In a 13‑ICU Korean cohort of 2,613 adults with sepsis, 45.3% received RBC transfusions during ICU days 1–3; mean nadir hemoglobin on the transfusion day was 8.8 ± 1.7 g/dL.
– Transfusion was more likely in patients with greater physiologic derangement (higher SAPS 3, septic shock, higher lactate, multi‑vasopressor use, coagulopathy, renal replacement therapy).
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