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Beyond Stenosis: Why Quantitative Plaque Volume Is the New Frontier in Cardiovascular Risk Assessment

MedXY Editorial Team•Feb 22, 2026•Cardiology
cardiovascular riskCCTAcoronary artery disease

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Quantitative plaque measures derived from coronary computed tomographic angiography (CCTA) significantly enhance the prediction of major adverse cardiovascular events (MACE) in patients without a prior diagnosis of coronary artery disease (CAD).

Total plaque burden (TPB) and noncalcified plaque burden (NCPB) are independent predictors of MACE, even after adjusting for traditional clinical risk factors and qualitative CCTA findings.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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