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Cardiology

Beyond Stenosis: The Prognostic Impact of Quantitative Plaque Volumetrics in Early Coronary Artery Disease

This review synthesizes findings from a PROMISE trial substudy, revealing that quantitative coronary plaque volume and burden are independent predictors of MACE in symptomatic outpatients, even when total plaque levels are low.

Mar 11, 2026
Cardiology

Beyond Stenosis: Why Quantitative Plaque Volume Is the New Frontier in Cardiovascular Risk Assessment

A substudy of the PROMISE trial demonstrates that quantitative plaque measures on CCTA—specifically total and noncalcified plaque burden—independently predict major adverse cardiovascular events in symptomatic outpatients, offering a precis

Feb 22, 2026Sign in to read
Cardiology

Coronary CT Angiography Modestly Improves Prediction of First Coronary Events Beyond Risk Scores and CAC

In a Swedish cohort of 24,791 adults aged 50–64, adding CCTA-derived measures of coronary atherosclerosis to pooled cohort equations and coronary artery calcium score modestly improved prediction of first coronary events over ~8 years.

Nov 10, 2025
Cardiology

Advancing Noninvasive Imaging in Assessing Hemodynamic Significance of Right Coronary Artery Anomalies

This article reviews a prospective study evaluating noninvasive anatomical and functional imaging methods to determine hemodynamic significance in right anomalous aortic origin of a coronary artery (R-AAOCA), proposing a stepwise diagnostic

Sep 27, 2025

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