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PRAETORIAN-DFT Trial Validates Omission of Defibrillation Testing in S-ICD Implantation

MedXY Editorial Team•Apr 28, 2026•Cardiology
Defibrillation testingPRAETORIAN scoreSubcutaneous ICD

Background

Subcutaneous implantable cardioverter-defibrillators (S-ICDs) have emerged as a vital tool in preventing sudden cardiac death (SCD) in high-risk patients. Unlike traditional transvenous ICDs, S-ICDs avoid intravascular lead complications but require precise subcutaneous positioning to ensure effective defibrillation. Historically, defibrillation (DF) testing has been recommended post-implantation to verify shock efficacy. However, DF testing carries risks, including hemodynamic instability and, in rare cases, death. The PRAETORIAN score, derived from chest X-ray analysis, was developed to predict DF success without the need for invasive testing. The PRAETORIAN-DFT trial aimed to validate this approach.

Study Design

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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Comparative Efficacy, Safety, and Complications of Subcutaneous Versus Transvenous Implantable Cardioverter-Defibrillators: Insights from the PRAETORIAN and ATLAS Trials and Meta-AnalysesThis review synthesizes randomized trial data comparing subcutaneous and transvenous ICDs, highlighting differences in inappropriate shocks, device-related complications, and shock efficacy, underscoring clinical considerations for ICD seleDec 25, 2025Long-Term Safety of Subcutaneous vs. Transvenous ICDs: Results from the PRAETORIAN-XL TrialThe PRAETORIAN-XL trial shows subcutaneous ICDs have fewer major and lead-related complications than transvenous ICDs over 8 years, suggesting S-ICD as a safer option for patients without pacing needs.Oct 3, 2025
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