Long-Term Safety of Subcutaneous vs. Transvenous ICDs: Results from the PRAETORIAN-XL Trial

Highlight

– The PRAETORIAN-XL trial provides the longest follow-up comparison (median 87.5 months) between subcutaneous ICD (S-ICD) and transvenous ICD (TV-ICD) regarding device-related complications.
– No significant difference was observed in the overall incidence of device-related complications.
– TV-ICDs were associated with significantly higher rates of major complications and lead-related issues.
– S-ICD should be considered a preferred option in patients without pacing indications.

Study Background and Disease Burden