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Immediate Versus Staged Complete Revascularisation in STEMI with Multivessel Disease: Insights from the OPTION-STEMI Trial

MedXY Editorial Team•Oct 8, 2025•Cardiology
Multivessel DiseasePCISTEMI

Highlight

– Immediate complete revascularisation during index STEMI admission was not proven non-inferior to staged revascularisation.
– At 1 year, primary composite outcomes (death, non-fatal MI, unplanned revascularisation) were similar but numerically higher in immediate group.
– Safety profiles, including stroke, bleeding, and contrast-induced nephropathy, were comparable, but cardiogenic shock was more frequent with immediate revascularisation.
– Results may influence guideline recommendations on timing of non-culprit lesion PCI in STEMI with multivessel disease.

Study Background and Disease Burden

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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