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IL-13 Inhibition with Cendakimab: A New Frontier in Eosinophilic Esophagitis Management

MedXY Editorial Team•Dec 31, 2025•Allergy & Immunology
CendakimabEosinophilic EsophagitisIL-13type 2 inflammation

Highlights

Cendakimab significantly reduced the frequency of dysphagia days compared to placebo at 24 weeks, achieving a mean reduction of 6.1 days.

Histologic response (≤6 eosinophils per high-power field) was achieved in 28.6% of patients receiving cendakimab once weekly, compared to only 2.2% in the placebo group.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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Add-on dupilumab significantly improves health-related quality of life and respiratory symptoms in COPD patients with type 2 inflammation, according to pooled results from the BOREAS and NOTUS phase 3 trials.
Oct 8, 2025
Type 2 Inflammation Biomarkers and Dupilumab Response in COPD: Insights from the BOREAS Phase 3 TrialDupilumab significantly reduced type 2 inflammation biomarkers and exacerbation risk in COPD patients with elevated eosinophils, highlighting the value of biomarker-driven therapy.Oct 1, 2025