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Genetic Liability for Suicide Attempt Is Linked to Aggression and Environmental Stressors: New Insights into Polygenic Risk

MedXY Editorial Team•Feb 12, 2026•news
polygenic riskpsychiatry

Highlights

Polygenic risk scores (PGS) for suicide attempts are significantly associated with suicidal behavior in both live and postmortem cohorts, with odds ratios of 1.35 and 1.34, respectively.

Higher genetic liability for suicide attempts is positively correlated with lifetime aggression and depression severity, but negatively correlated with hostility.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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