Enhanced Exercise Rehabilitation via Tailored Adherence Support Improves Outcomes in Vertebral Fragility Fractures: Insights from the OPTIN Randomised Controlled Trial

Highlight

• Adding tailored adherence support to exercise rehabilitation significantly improves mobility and walking capacity in people with vertebral fragility fractures (VFF).
• The OPTIN trial demonstrated clinically meaningful gains in Timed-Up and Go (TUG) and 6-minute walk test (6MW) outcomes at 12 months.
• Integrated adherence interventions using motivational interviewing, goal setting, and behavior change techniques can enhance long-term exercise engagement.
• No significant adverse events were reported, confirming the safety of the enhanced rehabilitation approach.

Study Background