Coronary Collaterals Attenuate Chest Pain in Stable Angina: Evidence From an Invasive Placebo‑Controlled N‑of‑1 Study
Highlights
– In 51 patients with severe single‑vessel coronary disease, greater collateral flow was strongly associated with more physiological ischemia (lower FFR/iFR) but with lower experimentally provoked chest pain intensity.
– Daily angina frequency showed little correlation with invasive physiologic indices (FFR, iFR), suggesting collaterals help explain the commonly observed mismatch between stenosis severity and symptoms.
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.